Histocompatibility antigens on astrocytoma cells.

Histocompatibility antigens on astrocytoma cells.

Biopsies tumour cells from astrocytoma-bearing patients were grown in primary culture for 3-5 days. Both low and high grade tumours were represented in the study. The cultured cells could be shown to express the HLA-A and -B antigens using a multispecific allo-antiserum and a rabbit anti-beta-2 microglobulin antibody. The tumour cells were negative for the HLA-DR determinants when tested with e...

48 Histocompatibility Antigens on Schistosomula

Schistosomiasis is an excellent example of the evasion of the immune response by a parasite. The trematode worms responsible for this disease can survive for many years inside the blood vessels of vertebrate hosts and are apparently undisturbed by the potent humoral and cell-mediated responses which they have been shown to induce. Several mechanisms have been postulated to explain the survival ...

Hemopoietic Progenitor Cells Minor Histocompatibility Antigens on Canine

Expression of major histocompatibility antigens on pancreatic islet cells.

Insulin-dependent diabetes mellitus is often accompanied by manifestations of autoimmunity and is frequently associated with certain HLA haplotypes, predominantly DR3 and DR4. Because the major histocompatibility antigens are important determinants of the immune response in various tissues, we have investigated their expression on the pancreatic islet cells. Human, mouse, or rat islets of Lange...

Frequency of Major Histocompatibility Antigens Class I in Mazandaran Province

 Background and purpose: Major histocompatibility antigens are the most polymorphic components of the immune system. The purpose of this study was to determine the frequency of human leukocyte antigens (HLA) in a population in Mazandaran province, Iran. Materials and methods: In a cross sectional study, peripheral blood samples were obtained from 550 people in Immunogenetics Research Center af...